Predictive Risk Model for the Development of Encephalopathy in Patients with Nutritional Pancreatic Necrosis

The objective: to develop a predictive model for assessing the risk of developing encephalopathy (EP) in patients with nutritional pancreatic necrosis. Subjects and Methods. A single-center prospective cohort study was conducted at Faculty Surgery Clinic Volgograd State Medical University from 2010 2020. Logistic regression analysis used build predicting EP. Results. total 429 were included study. It determined that majority EP manifested first three days after hospitalization. statistically significant correlation clinical demographic variables showed an increase severity patient's condition (according SOFA scale) by 1 point increased 1.9 times, bilirubin levels μmol/l, urea mmol/l AED 8.0% 28.0%, respectively. In non-alcoholic necrosis, compared alcoholic genesis disease, when using early (before day 3) enteral nutrition, there reduction 175.5% 137% cases. specificity sensitivity 78.7% 82.8%, Conclusions. nurtitional condition, progression signs liver kidney failure significantly At same time, nutrition contributed this complication. presented is recommended be routine practice.